For the process chemist, solving process problems early is becoming increasingly important. More demanding project timelines cannot be met at the expense of quality. Parallel chemistry is now providing a way to progress projects quickly and thoroughly, and to help minimise the chances of suffering expensive surprises in later development.
Ten individually controlled reactors for total experimental freedom
- Excellent access to reaction variables and precise reactor control make Amigo an invaluable tool to execute DoE protocols.
- Ideal for process screening and optimization. Progress different boiling point solvents at reflux simultaneously.
- Once a process has been optimized, Amigo can be used to confirm robustness to help minimize the possibility of production failures.
- Reaction volumes as small as 0.25ml and up to 20ml mean that extensive studies can be completed without consuming large amounts of expensive starting materials.
Explore more experimental factors – fast! Solvents, Reagents, Catalysts, Temperature, Stoichiometry, etc.
The Integrity 10™ reactor block offers a wide temperature range and powerful magnetic stirring. The block technology, in combination with our efficient reflux and inerting manifold has been proven with a wide range of chemistries including the following:
| Reaction type | Comments |
|---|---|
| Pd catalysed coupling | Air/water sensitive |
| Michael addition | Air sensitive |
| N-Alkylation | Aggressive reagents |
| Desilylation | Aggressive reagents |
| Lewis acids (TiCl4) | Aggressive reagents, Air/water sensitive |
| Strong bases BuLi, LDA | Aggressive reagents, Air/water sensitive |
| Cyclisation | Homogeneous |
| Aromatisation | Homogeneous |
| Grignards | Aggressive reagents, Air/water sensitive |
| Reduction and oxidation | Heterogeneous |
| Hydrogenation | Caution |